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A hyperintensity or T2 hyperintensity is an area of high intensity on types of magnetic resonance imaging (MRI) scans of the brain of a human or of another mammal that reflect lesions produced largely by demyelination and axonal loss.
Inversion recovery is a magnetic resonance imaging sequence that provides high contrast between tissue and lesion. It can be used to provide high T1 weighted image, high T2 weighted image, and to suppress the signals from fat, blood, or cerebrospinal fluid (CSF). [1]
There are two tests that can provide a definite diagnosis of myelomalacia; magnetic resonance imaging (MRI), or myelography. [8] Diffuse hyperintensity on T2-weighted imaging, and hypointensity on T1-weighted imaging of the spinal cord can be an indication of the onset or progression of myelomalacia
Normally two different kind of lesions appear on a normal MRI: T2-hypertense lesions and T1-hypointense. The first one are demyelinating lesions and appear brighter than the surroundings in T2-MRI. The T1-hypointense are areas less dense than the surrounding NAW, and appear black on T1-MRI. They are mainly axonal degeneration areas.
T1 weighted: T1: Measuring spin–lattice relaxation by using a short repetition time (TR) and echo time (TE). Lower signal for more water content, [1] as in edema, tumor, infarction, inflammation, infection, hyperacute or chronic hemorrhage. [2] High signal for fat [1] [2] High signal for paramagnetic substances, such as MRI contrast agents [2]
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields , magnetic field gradients, and radio waves to form images of the organs in the body.
MRI is also highly sensitive to marrow abnormalities surrounding the fracture line, which appear as hypointensity on T1 W images and hyperintensity on fluid-sensitive sequences. Such signal changes are thought to be a combination of bone marrow edema, intraosseous haemorrhage, and/or granulation tissue and help to identify even undisplaced ...
Additional MRI findings for absent/unknown AQP4-IgG Optic neuritis: Either 1) brain MRI showing normal findings or only nonspecific white matter lesions, or 2) optic nerve MRI showing T2-hyperintensity, or T1 enhancing lesion, greater than 1/2 optic nerve length or involving optic chiasm Acute myelitis