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Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]
Rapid eye movement sleep (REM sleep or REMS) is a unique phase of sleep in mammals (including humans) and birds, characterized by random rapid movement of the eyes, accompanied by low muscle tone throughout the body, and the propensity of the sleeper to dream vividly. The core body and brain temperatures increase during REM sleep and skin ...
Sleep paralysis is associated with sleep-related hallucinations. [22] Predisposing factors for the development of recurrent isolated sleep paralysis are sleep deprivation, an irregular sleep-wake cycle, e.g. caused by shift work, or stress. [22] A possible cause could be the prolongation of REM sleep muscle atonia upon awakening. [34]
RBD is a sleep disorder characterized by the loss of normal skeletal muscle atonia during REM sleep and is associated with prominent motor activity and vivid dreaming. [ 9 ] Symptomatic RBD can also be associated with narcolepsy , Guillain–Barré syndrome , limbic encephalitis , and Morvan's syndrome .
REM sleep, also known as paradoxical sleep, represents a smaller portion of total sleep time. It is the main occasion for dreams (or nightmares), and is associated with desynchronized and fast brain waves, eye movements, loss of muscle tone, [20] and suspension of homeostasis. [21] The sleep cycle of alternate NREM and REM sleep takes an ...
Disorders of arousal (from non-REM sleep) - Confusional arousals 327.41 G47.51 - Sleepwalking 307.46 F51.3 - Sleep terrors 307.46 F51.4 Parasomnias usually associated with REM sleep - REM sleep behavior disorder (including parasomnia overlap disorder and status dissociatus) 327.42 G47.52 - Recurrent isolated sleep paralysis 327.43 G47.53
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