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In clinical trials, the most common adverse events which occurred at a rate ≥5% and ≥1.5 times placebo included paraesthesia (tingling in fingers/toes), dizziness, altered taste, insomnia, constipation, and dry mouth.
This could slowly increase each week until a maximum dose of 3mg a day. ... Qsymia. Qsymia is a combo of topiramate and phentermine, which is an appetite suppressant. You take one tablet each morning.
Qsymia Phentermine is a substituted amphetamine and topiramate has an unknown mechanism of action ... (highest dose studied) Retatrutide: GLP-1, GIP, ...
A clinical trial looking at the effects of semaglutide on adults with obesity found that people taking a 2.4-milligram dose (once per week) lost about five pounds in four weeks. ... (Qsymia) is ...
If needed, your dose could increase in 2.5mg increments, up to a maximum dose of 15mg. You’ll spend four weeks on each dose before increasing it again. ... Qsymia (phentermine-topiramate ...
The maximum dose is used, rather than a lower dose, to reduce the number of test subjects (and, among other things, the cost of testing), to detect an effect that might occur only rarely. This type of analysis is also used in establishing chemical residue tolerances in foods. Maximum tolerated dose studies are also done in clinical trials.
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