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Cellular differentiation is the process in which a stem cell changes from one type to a differentiated one. [2] [3] Usually, the cell changes to a more specialized type. Differentiation happens multiple times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types.
Directed differentiation is a bioengineering methodology at the interface of stem cell biology, developmental biology and tissue engineering. [1] It is essentially harnessing the potential of stem cells by constraining their differentiation in vitro toward a specific cell type or tissue of interest. [ 2 ]
AP-2 complex. The AP2 adaptor complex is a multimeric protein that works on the cell membrane to internalize cargo in clathrin-mediated endocytosis. [1] It is a stable complex of four adaptins which give rise to a structure that has a core domain and two appendage domains attached to the core domain by polypeptide linkers.
In developmental biology, pattern formation refers to the generation of complex organizations of cell fates in space and time. The role of genes in pattern formation is an aspect of morphogenesis , the creation of diverse anatomies from similar genes, now being explored in the science of evolutionary developmental biology or evo-devo.
The process of producing new definitions by extending existing definitions is commonly known as differentiation (and also as derivation).The reverse process, by which just part of an existing definition is used itself as a new definition, is called abstraction; the new definition is called an abstraction and it is said to have been abstracted away from the existing definition.
Niche microdifferentiation is the process a species undergoes to reach genetic diversity within that species; it is the process by which an ecotype is created. This process is regulated by various environmental influences whether they be morphological, spatial, and/or temporal.
How nature sets the disproportionate numbers of particles remain unclear, but can be found using the theory of diffusion. One example is the number of neurotransmitters around 2000 to 3000 released during synaptic transmission, that are set to compensate the low copy number of receptors, so the probability of activation is restored to one. [19 ...
The human Y chromosome showing the SRY gene which codes for a protein regulating sexual differentiation. Sexual differentiation in humans is the process of development of sex differences in humans. It is defined as the development of phenotypic structures consequent to the action of hormones produced following gonadal determination. [1]