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A rough-skinned newt underwater A rough-skinned newt at Brice Creek in Oregon. Throughout much of the newt's range, the common garter snake (Thamnophis sirtalis) has been observed to exhibit resistance to the tetrodotoxin produced in the newt's skin. While in principle the toxin binds to a tube-shaped protein that acts as a sodium channel in ...
The diagnosis of pufferfish poisoning is based on the observed symptomatology and recent dietary history. [58] Symptoms typically develop within 30 minutes of ingestion, but may be delayed by up to four hours; however, if the dose is fatal, symptoms are usually present within 17 minutes of ingestion. [51]
The array of symptoms typically seen in carbamate poisoning include both muscarinic and nicotinic symptoms. [1] Muscarinic receptor effects include: Bradycardia, or reduced heart rate; Bronchospasm, or tightening of the bronchioles of the lungs; Miosis, or constriction of the pupils; Vomiting and abdominal pain; Diarrhea; Excessive sweating and ...
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
Ergotism (pron. / ˈ ɜːr ɡ ə t ˌ ɪ z ə m / UR-gət-iz-əm) is the effect of long-term ergot poisoning, traditionally due to the ingestion of the alkaloids produced by the Claviceps purpurea fungus—from the Latin clava "club" or clavus "nail" and -ceps for "head", i.e. the purple club-headed fungus—that infects rye and other cereals, and more recently by the action of a number of ...
Pyrrolizidine alkaloidosis poisoning in the United States has remained moderately rare among humans. The most common reports are the outcome of the misuse of medicinal home remedies, or the alkaloids are present in food and drink substances such as milk and honey when the animal carriers were exposed to the toxins.
The Coastal Range newt produce a potent poison called tetrodotoxin from specialized glands in their skin. Ingestion of this poison by handling or eating them causes severe neurological symptoms and, in some instances, death from respiratory or cardiac failure. The toxin found in juveniles is several times more potent than that in adults.
Specific treatments for acute pesticide poisoning are often dependent on the pesticide or class of pesticide responsible for the poisoning. However, there are basic management techniques that are applicable to most acute poisonings, including skin decontamination, airway protection, gastrointestinal decontamination, and seizure treatment.