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PF-05089771 is a selective, small-molecule Na v 1.7 and Na v 1.8 voltage-gated sodium channel blocker under development by Pfizer as a novel analgesic. [1] [2] [3] As of June 2014, it has completed phase II clinical trials for wisdom tooth removal and primary erythromelalgia. [4]
Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD).
4-Methylpregabalin is a drug developed by Pfizer and related to pregabalin, which similarly acts as an analgesic with effectiveness against difficult to treat "atypical" pain syndromes such as neuropathic pain.
Pfizer Inc. (NYSE: PFE) has announced that the U.S. Food and Drug Administration approved its drug candidate called XELJANZ. The treatment here is for rheumatoid arthritis and this is the 5 mg ...
PD-217,014 is a drug developed by Pfizer and related to gabapentin, which similarly binds to the α 2 δ calcium channels (1 and 2).It was developed as a potentially more potent successor to gabapentin and pregabalin, along with several other analogues such as atagabalin and 4-methylpregabalin, but while PD-217,014 produces visceral analgesic effects in animal studies with higher potency and ...
Parke-Davis developed a drug called pregabalin, which is related in structure to gabapentin, as a successor to gabapentin. [159] Another similar drug atagabalin has been unsuccessfully tried by Pfizer as a treatment for insomnia. [160] A prodrug form (gabapentin enacarbil) [161] was approved by the U.S. Food and Drug Administration (FDA).
The drug, branded as Velsipity and chemically known as etrasimod, was the key asset that Pfizer picked up in its $6.7 billion deal for Arena Pharmaceu US FDA approves Pfizer's inflammatory bowel ...
This is the first class of non-opioid pain medication approved to treat moderate to severe acute pain approved by the FDA in more than 20 years. FDA approves new type of non-opioid pain medication ...
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