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Ankle clonus. Clonus is a set of involuntary and rhythmic muscular contractions and relaxations. Clonus is a sign of certain neurological conditions, particularly associated with upper motor neuron lesions involving descending motor pathways, and in many cases is accompanied by spasticity (another form of hyperexcitability). [1]
[15] [41] During pregnancy brisk or hyperactive reflexes are common, however, ankle clonus is a sign of neuromuscular irritability that usually reflects severe pre-eclampsia and also can precede eclampsia. [93] Magnesium sulfate is used to prevent convulsions in cases of severe pre-eclampsia.
Leg cramps – Leg cramps (involuntary spasms of the calf muscles) can affect between 30% and 50% of pregnant women and most commonly occur in the last three months of pregnancy. [21] Leg cramps typically last only for a few seconds, however they can be extremely painful and last for minutes. [22]
Musculoskeletal disorders include lower-back pain, leg cramps, and hip pain. Pregnant women fall at a similar rate (27%) to women over age of 70 years (28%). Most of the falls (64%) occur during the second trimester. Additionally, two-thirds of falls are associated with walking on slippery floors, rushing, or carrying an object. [38]
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A person with spastic CP will commonly show, in addition to higher muscle tone, persistent primitive reflexes, greater stretch reflexes, plantar reflex, and ankle clonus. [10] A third of people with cerebral palsy have seizures - this is most common in spastic CP. [11] Audiovisual, cognitive compromise and behavioral disorders can occur.
Low birth weight may be a result of preterm birth.. Low birth weight (LBW) is defined by the World Health Organization as a birth weight of an infant of 2,499 g (5 lb 8.1 oz) or less, regardless of gestational age. [1]
Neurologic examination of individuals with this mutation may show dysmetria in the upper extremities, hyperreflexia, distal amyotrophy and ankle clonus, in addition to spasticity, weakness and dysarthria. [10]