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Wilms' tumor or Wilms tumor, [3] also known as nephroblastoma, is a cancer of the kidneys that typically occurs in children (rarely in adults), [4] and occurs most commonly as a renal tumor in child patients. [5] [6] It is named after Max Wilms, the German surgeon (1867–1918) who first described it. [7]
WAGR syndrome (also known as WAGR complex, Wilms tumour-aniridia syndrome, aniridia-Wilms tumour syndrome) is a rare genetic syndrome in which affected children are predisposed to develop Wilms' tumour (a tumour of the kidneys), aniridia (absence of the coloured part of the eye, the iris), genitourinary anomalies, and mental retardation. [1]
This is an accepted version of this page This is the latest accepted revision, reviewed on 13 February 2025. Medical condition Kidney cancer Other names Renal cancer Micrograph showing the most common type of kidney cancer (clear cell renal cell carcinoma). H&E stain. Specialty Oncology nephrology Urology Symptoms Blood in the urine, lump in the abdomen, back pain Usual onset After the age of ...
TUCSON, Ariz., June 11 (Reuters) -- An Arizona woman was recovering at home on Wednesday after having a 47.5-pound (21.5 kg) tumor removed from her abdomen during life-saving surgery, doctors said ...
Desmoid tumors may occur in the head and neck, more commonly among children, and tend to be more aggressive than in other extra-abdominal locations. These tumors constitute up to 23% of extra-abdominal cases. [16] Treatment is typically more aggressive due to the increased dangers of a tumor in the area. [29] [34]
Inactivation of WT1 causes Wilms tumour, and Denys-Drash syndrome (DDS), leading to nephropathy and genital abnormalities. The WT1 protein has been found to bind a host of cellular factors, e.g. p53, a known tumor suppressor. [7] [12] [13] [14] Despite the name, WT1 mutation is found in only about 5-10% of Wilms Tumor cases. [15]
In this study, the commonest sites of tumor occurrence were the lower limb and hip (22% of cases), upper limb and shoulder (12% of cases), and head, face, and neck (9% of cases). [7] Another recent study of 25 patients found the commonest sites of IMT were the abdomen (40% of cases) and lung/thoracic wall (32% of cases). [13]
The NWTS was created with the purpose of improving survival of children with Wilms' tumor. NWTS studies were conducted at over 250 pediatric oncology treatment centers in the United States, Canada, and other countries. Approximately 70-80% of patients with Wilms' tumor were enrolled on NWTS treatment protocols, totalling 440 patients per year.