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Like any injection, cortisone shots come with the risk of infection. Additionally, they may cause side effects such as increased blood sugar levels, skin thinning, or changes in pigmentation ...
Dr. Carrie Jose, in her latest Health and Wellness column, provides questions to ask before getting a cortisone injection
Cortisone is a pregnene (21-carbon) steroid hormone.It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug. Cortisol is converted by the action of the enzyme corticosteroid 11-beta-dehydrogenase isozyme 2 into the inactive metabolite cortisone, particularly in the kidneys.
In osteoarthritis, joint injection of glucocorticoids (such as hydrocortisone) leads to short term pain relief that may last between a few weeks and a few months. [5] Injections of hyaluronic acid have not produced improvement compared to placebo for knee arthritis, [6] [7] but did increase risk of further pain. [6]
Due to the extensive risk of side effects associated with the use of corticosteroids, it is generally recommended for short term therapy. For example, during a flare-up or an episode of arthritic symptoms, short-term corticosteroids are administered to rapidly decrease inflammation of the joints.
When an infection gets into the knee joint, “the knee quickly becomes really swollen, red, and hot,” says Dr. Gladstone. If untreated, infection can affect the whole body, causing fevers and ...
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