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The Purdue Pegboard Test is a psychomotor test of manual dexterity and bimanual coordination. [1] The test involves two different abilities: gross movements of arms, hands, and fingers, and fine motor extremity, also called "fingerprint" dexterity. [2]
The specific molecular mechanism that underpins this movement disorder is not well known. [2] However, most researchers suggest that it follows an autosomal dominant genetic inheritance pattern in which mutations in certain genes give rise to structural abnormalities in nervous system networks responsible for voluntary skeletal muscle movement, which, in turn, result in the functional movement ...
Bimanual coordination involves the coordination of two arms in bimanual action, which allows two hands to move simultaneously to do tasks. [1] Examples of bimanual coordination include clapping hands, opening the cap of a bottle with two hands or typing words on a keyboard with both hands.
The first symptoms are often mistakenly attributed to aging or stress. [34] Detailed neuropsychological testing can reveal mild cognitive difficulties up to eight years before a person fulfills the clinical criteria for diagnosis of Alzheimer's disease. [35] These early symptoms can affect the most complex activities of daily living. [36]
An estimated 70,800 people in the UK are living with young onset dementia, where symptoms begin before the age of 65
Dementia with Lewy bodies (DLB) is a type of dementia, a group of diseases involving progressive neurodegeneration of the central nervous system. [11] It is one of the two Lewy body dementias, along with Parkinson's disease dementia. [12] Dementia with Lewy bodies can be classified in other ways.