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Azacitidine is a chemical analogue of the nucleoside cytidine, which is present in DNA and RNA.It is thought to have antineoplastic activity via two mechanisms – at low doses, by inhibiting of DNA methyltransferase, causing hypomethylation of DNA, [16] and at high doses, by its direct cytotoxicity to abnormal hematopoietic cells in the bone marrow through its incorporation into DNA and RNA ...
While COVID-19 refers to the disease and SARS-CoV-2 refers to the virus which causes it, referring to the "COVID-19 virus" has been accepted. [9] [25] [29] Reference to SARS-CoV-2 as "the coronavirus" has become somewhat accepted despite such use implying that there is only one coronavirus species. Similarly, use of "COVID" for the disease (if ...
A term for COVID-19 used by former United States president Donald Trump to emphasize that the pandemic started in China. Comirnaty. Main article: Comirnaty. The commercial name for the FDA approved COVID-19 vaccine from Pfizer, released August 21, 2021. It also has several other names or designators used on the actual vials. Community transmission
New COVID-19 variants continue to pop up. Experts explain how many COVID variants there are, important subvariants, and the evolution of SARS-CoV-2 virus. A Comprehensive List of All of the COVID ...
A study of samples collected in Manaus between November 2020 and January 2021, indicated that the Gamma variant is 1.4–2.2 times more transmissible and was shown to be capable of evading 25–61% of inherited immunity from previous coronavirus diseases, leading to the possibility of reinfection after recovery from an earlier COVID-19 ...
During the initial outbreak in Wuhan, China, various names were used for the virus; some names used by different sources included "the coronavirus" or "Wuhan coronavirus". [ 27 ] [ 28 ] In January 2020, the World Health Organization (WHO) recommended "2019 novel coronavirus" (2019-nCoV) [ 5 ] [ 29 ] as the provisional name for the virus.
Transmission and life-cycle of SARS-CoV-2 causing COVID-19. Coronaviruses vary significantly in risk factor. Some can kill more than 30% of those infected, such as MERS-CoV, and some are relatively harmless, such as the common cold. [49] Coronaviruses can cause colds with major symptoms, such as fever, and a sore throat from swollen adenoids. [91]
The Oxford–AstraZeneca COVID-19 vaccine, sold under the brand names Vaxzevria [6] and Covishield, [7] is a viral vector vaccine [8] produced by the British University of Oxford, British-Swedish company AstraZeneca, and the Coalition for Epidemic Preparedness Innovations.