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  2. History of general anesthesia - Wikipedia

    en.wikipedia.org/wiki/History_of_general_anesthesia

    On 30 March 1842, he administered diethyl ether by inhalation to a man named James Venable, in order to remove a tumor from the man's neck. [102] Long later removed a second tumor from Venable, again under ether anesthesia. He went on to employ ether as a general anesthetic for limb amputations and childbirth. Long, however, did not publish his ...

  3. Guedel's classification - Wikipedia

    en.wikipedia.org/wiki/Guedel's_classification

    Since 1982, ether is not used in the United States. [7] Now, because of the use of intravenous induction agents with muscle relaxants and the discontinuation of ether, elements of Guedel's classification have been superseded by depth of anaesthesia monitoring devices such as the BIS monitor; [5] however, the use of BIS monitoring remains ...

  4. Theories of general anaesthetic action - Wikipedia

    en.wikipedia.org/wiki/Theories_of_general...

    The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.

  5. Joseph Thomas Clover - Wikipedia

    en.wikipedia.org/wiki/Joseph_Thomas_Clover

    Joseph Thomas Clover (born 28 February 1825; baptised 7 May 1825 – 27 September 1882) [2] was an English doctor and innovator of anaesthesia.He invented a variety of pieces of apparatus to deliver anaesthetics, including ether and chloroform, safely and controllably.

  6. Edward Gilbert Abbott - Wikipedia

    en.wikipedia.org/wiki/Edward_Gilbert_Abbott

    The MGH Department of Anesthesia, Critical Care and Pain Medicine traces its roots back to the October 16, 1846 public demonstration of medical ether. Edward Gilbert Abbott (1825–1855) was the patient upon whom William T. G. Morton first publicly demonstrated the use of ether as a surgical anesthetic .

  7. Crawford Long - Wikipedia

    en.wikipedia.org/wiki/Crawford_Long

    Crawford Long U.S. postage stamp. Long was born in Danielsville, [3] Madison County, Georgia on November 1, 1815, to James and Elizabeth Long. [4] His father was a state senator, a merchant and a planter, and named his son after his close friend and colleague, Georgia statesman William H. Crawford.

  8. Horace Wells - Wikipedia

    en.wikipedia.org/wiki/Horace_Wells

    Ether Day – The Strange Tale of America's Greatest Medical Discovery and the Haunted Men Who Made It. New York: HarperCollins. ISBN 0060195231. Musto, David F., "They Inhaled", New York Times, August 12, 2001 (review of Ether Day) Downs, Michael (2018). The Strange and True Tale of Horace Wells, Surgeon Dentist: A Novel – Historical Fiction ...

  9. Desflurane - Wikipedia

    en.wikipedia.org/wiki/Desflurane

    Desflurane (1,2,2,2-tetrafluoroethyl difluoromethyl ether) is a highly fluorinated methyl ethyl ether used for maintenance of general anesthesia. Like halothane , enflurane , and isoflurane , it is a racemic mixture of ( R ) and ( S ) optical isomers ( enantiomers ).

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