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Cancer in cats is the leading cause of death among cats. It is caused by uncontrolled cell growth, and affects a wide range of cell types and organs in the body. Feline cancer initially manifests as a lump or bump on any part of the body.
Feline odontoclastic resorption lesion (FORL) is a syndrome in cats characterized by resorption of the tooth by odontoclasts, cells similar to osteoclasts. FORL has also been called Feline tooth resorption ( TR ), neck lesion , cervical neck lesion , cervical line erosion , feline subgingival resorptive lesion , feline caries , or feline cavity .
Cancers of the GI tract (esophageal, gastric, and colorectal) are on the rise. Over the last 30 years there has been an increase in incidence of adenocarcinoma of the esophagus, gastroesophageal junction, and gastric cardia. [3] Gastric cancer is the fourth most common malignant tumor and third most common cause of cancer related death.
Esophageal endoscopic ultrasound can provide staging information regarding the level of tumor invasion, and possible spread to regional lymph nodes. The location of the tumor is generally measured by the distance from the teeth. The esophagus (25 cm or 10 in long) is commonly divided into three parts for purposes of determining the location.
Aging in cats is the process by which cats change over the course of their natural lifespans. The normal lifespan of domestic cats is in the range of 13 to 20 years. As cats senesce, they undergo predictable changes in health and behavior. Dental disease and loss of olfaction are common as cats age, affecting eating habits.
Upper gastrointestinal bleeding can be caused by peptic ulcers, gastric erosions, esophageal varices, and rarer causes such as gastric cancer. The initial assessment includes measurement of the blood pressure and heart rate, as well as blood tests to determine the hemoglobin.
Barrett's esophagus is the dominant pre-malignant lesion of esophageal adenocarcinoma, [18] and has prevalent epigenetic alterations. [19] Esophageal squamous-cell carcinomas may occur as second primary tumors associated with head and neck cancer, due to field cancerization (i.e. a regional reaction to long-term carcinogenic exposure).
Chronic inflammation caused by H. pylori infection in the stomach and GERD in the esophagus are seen as the primary instigators of metaplasia and subsequent adenocarcinoma formation. Initially, the transformed epithelium resembles the small intestine lining; in the later stages it resembles the lining of the colon .