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The Sequenced Treatment Alternatives to Relieve Depression Study (STAR*D) Trial [13] also found that patients had low response rates to alternative compounds after the failure of the first antidepressant. [2] [14] Thus, a need for more rapid, yet prolonged, efficacy in treatment has stimulated further research on alternative treatment options.
In recent years, ketamine — a powerful anesthetic — has drawn more attention as a potential treatment for people seeking alternative therapies for depression, anxiety and other conditions.
The World Health Organisation has stated that depression is a leading cause of disability worldwide and a major contributor to the global burden of disease. [5] Stephen Ilardi has described depression as a "disease of civilisation", stating "We were never designed for the sedentary, indoor, sleep-deprived, socially-isolated, fast-food-laden, frenetic pace of modern life".
One behavioral activation approach to depression had participants create a hierarchy of reinforcing activities, rank-ordered by difficulty. Participants then tracked goals along with clinicians who used a token economy to reinforce success in moving through the hierarchy of activities, being measured before and after by the Beck Depression Inventory.
Sep. 29—Antidepressants and counseling are the most common ways for people to alleviate their depression symptoms. But for those who experience a form known as treatment-resistant depression ...
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