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Detailed Pyridostigmine dosage information for adults. Includes dosages for Myasthenia Gravis, Reversal of Nondepolarizing Muscle Relaxants and Nerve Agent Pretreatment; plus renal, liver and dialysis adjustments.
Indicated as a reversal agent or antagonist to neuromuscular blocking effects of nondepolarizing muscle relaxants. 0.1-0.25 mg/kg/dose IV. 10-20 mg generally effective; full recovery may...
Oral: Highly individualized dosing ranges: Immediate-release: 60 to 1,500 mg/day, usually 600 mg/day divided into 5 to 6 doses, spaced to provide maximum relief.
Each Mestinon ER tablet is 180 mg. If you’re prescribed the Mestinon ER tablets, the typical dosage is one to three tablets (180–540 mg) once or twice per day. If you’re taking two doses...
MESTINON is available in three dosage forms: raspberry-flavored, containing 60 mg pyridostigmine bromide per teaspoonful (5 mL). This form permits accurate dosage adjustment for children and “brittle” myasthenic patients who require fractions of 60 mg doses.
Usual daily maintenance dosage ranges from 60 mg to 1.5 g (average 600 mg). Extended-release tablets: Manufacturer suggests dosage of 180–540 mg 1–2 times daily (with ≥6 hours between doses). However, extended-release dosage form is generally used only at bedtime in patients who awaken at night or in the early morning with impairing weakness.
In addition, neostigmine or pyridostigmine may be given by injection as an antidote to certain types of muscle relaxants used in surgery. These medicines are available only with your doctor's prescription. This product is available in the following dosage forms:
10-20 mg generally effective; full recovery may occur as early as less than 15 minutes but may require greater than 30 minutes; To minimize side effects 0.6-1.2 mg intravenously (IV) atropine sulfate is recommended immediately before pyridostigmine; Pediatric: 0.1-0.25 mg/kg/dose intravenously (IV)
Pyridostigmine comes as a regular tablet, an extended-release (long-acting) tablet, and a syrup to take by mouth. It usually is taken once, twice, or several times a day, depending on the type of tablet. Your doctor may change your dose, depending on how you respond to the drug.
Each Pyridostigmine Bromide Tablet USP intended for oral administration contains 60 mg of pyridostigmine bromide USP. In addition, each tablet contains the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide and stearic acid.