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Myxedema (British English: myxoedema) is a term used synonymously with severe hypothyroidism.However, the term is also used to describe a dermatological change that can occur in hypothyroidism and (rare) paradoxical cases of hyperthyroidism.
Myxedematous psychosis, more commonly referred to as the myxedema madness is manifested through hypothyroidism which is a condition in where the thyroid gland does not produce enough thyroid hormones, some of the most common symptoms linked with both of these conditions include: Fatigue, Cold intolerance, Menstrual abnormalities, Decreased ...
Myxedema coma is an extreme or decompensated form of hypothyroidism and while uncommon, is potentially lethal. [1] [2] [3] A person may have laboratory values identical to a "normal" hypothyroid state, but a stressful event (such as an infection, myocardial infarction, or stroke) precipitates the myxedema coma state, usually in the elderly.
Close up of face, showing myxedematous facies, macroglossia, and skin mottling Close up showing abdominal distension and umbilical hernia. Congenital hypothyroidism, copper engraving, 1815
Papular mucinosis (also known as scleromyxedema, [1] [2] "generalized lichen myxedematosus" and "sclerodermoid lichen myxedematosus") is a rare skin disease. Localized and disseminated cases are called papular mucinosis or lichen myxedematosus while generalized, confluent papular forms with sclerosis are called scleromyxedema.
Pretibial myxedema is almost always preceded by the ocular signs found in Graves' disease. [3] It usually presents itself as a waxy, discolored induration of the skin—classically described as having a so-called peau d'orange (orange peel) appearance—on the anterior aspect of the lower legs, spreading to the dorsum of the feet, or as a non-localised, non-pitting edema of the skin in the ...
Numerous therapies have been attempted, with varying degrees of success, such as dermabrasion, CO2 laser, intralesional injections of corticosteroids or hyaluronidase, oral retinoids, psoralen ultraviolet A, and pimecrolimus. [5]
Lichen myxedematous is a group of cutaneous disorders considered mucinoses. [1] [2] Conditions included in this group are: [2] Generalized lichen myxedematosus; Localized lichen myxedematosus; Discrete papular lichen myxedematosus; Acral persistent papular mucinosis; Self-healing papular mucinosis; Self-healing juvenile cutaneous mucinosis