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Benign symmetric lipomatosis, also known as Madelung's disease, is an adult-onset skin condition characterized by extensive symmetric fat deposits in the head, neck, and shoulder girdle area. [1] The symmetrical fat deposits are made of unencapsulated lipomas , which distinguishes it from typical lipomatosis which has encapsulated lipomas that ...
Treatment is typically by observation or surgical removal. [1] Rarely, the condition may recur following removal, but this can generally be managed with repeat surgery. [1] They are not generally associated with a future risk of cancer. [1] Lipomas have a prevalence of roughly 2 out of every 100 people. [2]
Removal can include simple excision, endoscopic removal, or liposuction. [ 1 ] Other entities which are accompanied by multiple lipomas include Proteus syndrome , Cowden syndrome and related disorders due to PTEN gene mutations, benign symmetric lipomatosis ( Madelung disease ), Dercum's Disease, familial lipodystrophy , hibernomas , epidural ...
The only effective treatments for lipomas caused by familial multiple lipomatosis are liposuction or surgical removal. [6] Steroid injections may also be used to shrink the tumors by causing local fat atrophy. [7] Patients with the condition often seek removal when the lipomas are large, disfiguring, or cause pain. [2]
Spindle cell lipoma is most frequently located in the upper back, shoulder, or posterior neck subcutaneous layer. [3] Nonetheless, reports of it occurring in the mediastinum, hypopharynx, larynx, anterior neck, suprasellar region, esophagus, nasal vestibule, tongue, floor of mouth, vallecula, parotid gland, and breast have been made. [4]
Most cases of pleomorphic lipoma are seen in the subcutaneous tissue of the back, shoulder, and posterior neck. [2] Less commonly, it can also happen in odd places like the tongue, [3] vulva, [4] palm, [5] tonsillar fossa, [6] orbit, [7] and oral cavity. [8] The lesion usually presents as a subcutaneous lump that is circumscribed, like the ...
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Angiolipoma is a subcutaneous nodule with vascular structure, having all other features of a typical lipoma. They are commonly painful. [1]: 624 [2] Angiolipomas manifest as multiple painful subcutaneous nodules commonly on the upper limbs. The can occur sporadically, with a family history or after trauma.