Ads
related to: recombinant protein production in plants
Search results
Results From The WOW.Com Content Network
Protein production is the biotechnological process of generating a specific protein. It is typically achieved by the manipulation of gene expression in an organism such that it expresses large amounts of a recombinant gene .
The first recombinant plant-derived protein (PDP) was human serum albumin, initially produced in 1990 in transgenic tobacco and potato plants. [6] Open field growing trials of these crops began in the United States in 1992 and have taken place every year since.
Plant cell culture was used to produce FDA-approved glycosylated lysosomal protein-drug, and additional drug candidates. [11] Recent studies have shown that it may be possible to produce recombinant lysosomal proteins with microorganisms such as Escherichia coli and Saccharomyces cerevisiae. [12]
In this way, DNA injected into a plant is turned into recombinant DNA and manipulated. The favorable properties of plants are likely to make the plant systems a useful alternative for small, medium and large scale production throughout the development of new antibody-based pharmaceuticals. [7]
The plant-based vaccine production method works by isolating a specific antigen protein, one that triggers a human immune response from the targeted virus. A gene from the protein is transferred to bacteria, which are then used to “infect” plant cells. The plants then start producing the exact protein that will be used for vaccinations. [6]
The protein may be expressed as a fusion to the coat protein of the virus and is displayed on the surface of assembled viral particles, or as an unfused protein that accumulates within the plant. Expression in plant using plant vectors is often constitutive, [ 34 ] and a commonly used constitutive promoter in plant expression vectors is the ...
Ads
related to: recombinant protein production in plantsrndsystems.com has been visited by 10K+ users in the past month