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A motivation-enhancing drug, [2] [3] also known as a pro-motivational drug, [1] is a drug which increases motivation. [ 4 ] [ 1 ] Drugs enhancing motivation can be used in the treatment of motivational deficits , for instance in depression , schizophrenia , and attention deficit hyperactivity disorder (ADHD).
Giurgea stated that nootropic drugs should have the following characteristics: They should enhance learning and memory. They should enhance the resistance of learned behaviors or memories to conditions which tend to disrupt them (e.g. electroconvulsive shock, hypoxia). They should protect the brain against various physical or chemical injuries.
Endorphins (contracted from endogenous morphine) [1] [2] [3] are peptides produced in the brain that block the perception of pain and increase feelings of wellbeing. They are produced and stored in the pituitary gland of the brain.
Chemistry, not moral failing, accounts for the brain’s unwinding. In the laboratories that study drug addiction, researchers have found that the brain becomes conditioned by the repeated dopamine rush caused by heroin. “The brain is not designed to handle it,” said Dr. Ruben Baler, a scientist with the National Institute on Drug Abuse.
One in four U.S. adults suspects they may have ADHD and drugs are a first line of treatment for this condition. But what does research say about their impact on the brain and quality of life?
The brain includes several distinct dopamine pathways, one of which plays a major role in the motivational component of reward-motivated behavior. The anticipation of most types of rewards increases the level of dopamine in the brain, [4] and many addictive drugs increase dopamine release or block its reuptake into neurons following release. [5]