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BCG vaccine can be administered after birth intradermally. [7] BCG vaccination can cause a false positive Mantoux test. [19] The most controversial aspect of BCG is the variable efficacy found in different clinical trials, which appears to depend on geography. Trials in the UK consistently show a 60 to 80% protective effect.
Tuberculosis (TB) vaccines are vaccinations intended for the prevention of tuberculosis.Immunotherapy as a defence against TB was first proposed in 1890 by Robert Koch. [1] As of 2021, the only effective tuberculosis vaccine in common use is the Bacillus Calmette-Guérin (BCG) vaccine, first used on humans in 1921.
During active disease, some of these cavities are joined to the air passages and this material can be coughed up. It contains living bacteria and thus can spread the infection. Treatment with appropriate antibiotics kills bacteria and allows healing to take place. Upon cure, affected areas are eventually replaced by scar tissue.
Type 2 diabetes is the most common type of diabetes. Treatments include agents that (1) increase the amount of insulin secreted by the pancreas, (2) increase the sensitivity of target organs to insulin, (3) decrease the rate at which glucose is absorbed from the gastrointestinal tract, and (4) increase the loss of glucose through urination.
A 2000 Cochrane review containing 11 double-blinded, randomized control trials and 73,375 patients examined six and 12 month courses of isoniazid (INH) for treatment of latent tuberculosis. HIV positive and patients currently or previously treated for tuberculosis were excluded.
Current Diabetes Reports is a monthly peer-reviewed medical journal that publishes review articles on all aspects of diabetes. It was established in 2001 and is published by Springer Science+Business Media. The editor-in-chief is Jose C. Florez (Massachusetts General Hospital).