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Referring to a common salt of fluoride, sodium fluoride (NaF), the lethal dose for most adult humans is estimated at 5 to 10 g (which is equivalent to 32 to 64 mg elemental fluoride/kg body weight). [ 2 ] [ 3 ] [ 4 ] Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower (0.2–0.3 mg/kg or 10 to 15 ...
[9] [10] Hexafluoride Solution has been used to mitigate the adverse effects of chemical burns and counteract the effect of calcium precipitation [11] [self-published source], due to the triple effect of rinsing and diluting like water, neutralization of the hydrogen ions and chelation of the fluoride ions. However, further studies have found ...
Ingested fluoride forms hydrofluoric acid in the stomach. In this form, fluoride crosses cell membranes and then binds with calcium and interferes with various enzymes. Fluoride is excreted through urine. Fluoride exposure limits are based on urine testing, which is used to determine the human body's capacity for ridding itself of fluoride. [69 ...
Soluble fluoride salts, of which sodium fluoride is the most common, are toxic, and have resulted in both accidental and self-inflicted deaths from acute poisoning. [4] The lethal dose for most adult humans is estimated at 5 to 10 g (which is equivalent to 32 to 64 mg elemental fluoride per kg body weight).
Fluoride therapy is the use of fluoride for medical purposes. [2] Fluoride supplements are recommended to prevent tooth decay in children older than six months in areas where the drinking water is low in fluoride. [3] It is typically used as a liquid, pill, or paste by mouth. [4] Fluoride has also been used to treat a number of bone diseases. [5]
Halogenodermas are skin eruptions that result after exposure to halogen-containing drugs or substances. This may last several weeks after drug use is discontinued. This is because of the slow elimination rate of iodides and bromides. [1] Fluoroderma is a particular type of halogenoderma which is caused by fluoride.
In 2011, the U.S. Department of Health and Human Services launched the Gulf Long-term Follow-up Study through the National Institute of Environmental Health Sciences. As the largest, most comprehensive study of long-term health effects from an oil spill, the GuLF Study will collect health data on cleanup workers and track them for at least 5 years.
Skin absorption relates to the degree of exposure to and possible effect of a substance which may enter the body through the skin. Human skin comes into contact with many agents intentionally and unintentionally. Skin absorption can occur from occupational, environmental, or consumer skin exposure to chemicals, cosmetics, or pharmaceutical ...