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An upper respiratory tract infection (URTI) is an illness caused by an acute infection, which involves the upper respiratory tract, including the nose, sinuses, pharynx, larynx or trachea. [ 3 ] [ 4 ] This commonly includes nasal obstruction, sore throat, tonsillitis , pharyngitis , laryngitis , sinusitis , otitis media , and the common cold .
The common cold is an infection of the upper respiratory tract which can be caused by many different viruses. The most commonly implicated is a rhinovirus (30–80%), a type of picornavirus with 99 known serotypes. [33]
An infection of this type usually is further classified as an upper respiratory tract infection (URI or URTI) or a lower respiratory tract infection (LRI or LRTI). Lower respiratory infections, such as pneumonia, tend to be far more severe than upper respiratory infections, such as the common cold.
Upper respiratory tract infections (URTIs) often precede acute bronchitis, with overlapping symptoms including headache, nasal congestion, and sore throat. About a third of patients will experience a fever, but fevers due to acute bronchitis rarely rise above 100 °F (37.8 °C) or last longer than a few days. [ 14 ]
Pharyngitis is a type of upper respiratory tract infection. [7] Most cases are caused by a viral infection. [2] Strep throat, a bacterial infection, is the cause in about 25% of children and 10% of adults. [2] Uncommon causes include other bacteria such as gonococcus, fungi, irritants such as smoke, allergies, and gastroesophageal reflux disease.
Streptococcal pharyngitis, also known as streptococcal sore throat (strep throat), is pharyngitis (an infection of the pharynx, the back of the throat) caused by Streptococcus pyogenes, a gram-positive, group A streptococcus. [9] [10] Common symptoms include fever, sore throat, red tonsils, and enlarged lymph nodes in the front of the neck.
Inadequate oxygen supply to the tissue is one of the main concerns during severe bronchiolitis and oxygen saturation is often closely associated with both the need for hospitalization and continued length of hospital stay in children with bronchiolitis. [15] However, oxygen saturation is a poor predictor of respiratory distress. [9]
Pneumonia frequently starts as an upper respiratory tract infection that moves into the lower respiratory tract. [55] It is a type of pneumonitis (lung inflammation). [56] The normal flora of the upper airway give protection by competing with pathogens for nutrients.