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General imbalance theories of aging suggest that body systems, such as the endocrine, nervous, and immune systems, gradually decline and ultimately fail to function. The rate of failure varies system by system.
Immunological theory of aging; Log-normal theory of mortality; Membrane theory of aging; Mitochondrial Free Radical Theory of Aging; Mitochondrial Theory of Aging; Mutation accumulation theory of aging; Neuroendocrine theory of aging; Order to disorder theory of aging; Rate of living theory; Redundant DNA theory; Reliability theory of aging and ...
Ageing (or aging in American English) is the process of becoming older. The term refers mainly to humans , many other animals , and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal .
The metabolic stability theory of aging suggests it is the cells ability to maintain stable concentration of ROS which is the primary determinant of lifespan. [37] This theory criticizes the free radical theory because it ignores that ROS are specific signalling molecules which are necessary for maintaining normal cell functions. [37]
In 1954 Vladimir Dilman proposed hypothesis of aging that at first become known only in the USSR, as the elevation hypothesis. In 1968 it took the form and became known as the neuroendocrine theory of aging. [3] [4] [5]
In 1968 it took the form and became known as the neuroendocrine theory of aging. [38] [39] [40] 1956 Denham Harman proposed the free-radical theory of aging and demonstrated that free radical reactions contribute to the degradation of biological systems. [41] The theory is based on the ideas of Rebeca Gerschman and her colleagues put forward in ...
Selectivity theory (aging) Socioemotional selectivity theory; Stage-crisis view; Stem cell theory of aging; Stereotype embodiment theory; T. Telomere theory of aging; V.
Strength of natural selection plot as a function of age. The antagonistic pleiotropy hypothesis (APT) is a theory in evolutionary biology that suggests certain genes may confer beneficial effects early in an organism's life, enhancing reproductive success, while also causing detrimental effects later in life, contributing to the aging process.