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Stercoral ulcer is an ulcer of the colon due to pressure and irritation resulting from severe, prolonged constipation due to a large bowel obstruction, damage to the autonomic nervous system, or stercoral colitis. It is most commonly located in the sigmoid colon and rectum.
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Ulcerative colitis is a type of inflammatory bowel disease (IBD). [4] It is a long-term condition that results in inflammation and ulcers of the colon and rectum. [4] [5] The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia). Weight loss, fever, and anemia may also occur. Often, symptoms come on ...
Increased expression of ICAM-1 has been observed within the inflamed intestinal mucosa of people with ulcerative colitis, pouchitis and Crohn's, where ICAM-1 over production correlated with disease activity. [140] This suggests that ICAM-1 is a potential therapeutic target in the treatment of these diseases. [141] [142]
Stercoral perforation [1] is the perforation or rupture of the intestine's walls by its internal contents, such as hardened feces or foreign objects. Hardened stools may form in prolonged constipation or other diseases which cause obstruction of transit, such as Chagas disease, Hirschprung's disease, toxic colitis, hypercalcemia, and megacolon.
Its mechanism is incompletely understood. It is probably due to excessive production of nitric oxide, at least in ulcerative colitis. The prevalence is about the same for both sexes. [citation needed] In patients with HIV/AIDS, cytomegalovirus (CMV) colitis is the leading cause of toxic megacolon and emergency laparotomy. CMV may also increase ...
A perforated ulcer can be grouped into a stercoral perforation which involves a number of different things that cause perforation of the intestine wall. The first symptom of a perforated peptic ulcer is usually sudden, severe, sharp pain in the abdomen. [1] The pain is typically at its maximum immediately and persists.