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3D medical illustration depicting the TNM stages in breast cancer. Cancer staging can be divided into a clinical stage and a pathologic stage. In the TNM (Tumor, Node, Metastasis) system, clinical stage and pathologic stage are denoted by a small "c" or "p" before the stage (e.g., cT3N1M0 or pT2N0).
Blastomycosis in the lungs may present a variety of symptoms, or no symptoms at all. [8] If symptoms are present they may range from mild pneumonia resembling a pneumococcal infection to acute respiratory distress syndrome (ARDS). [8] Common symptoms include fever, chills, headache, coughing, difficulty breathing, chest pain, and malaise. [8]
One example is an enzyme called tyrosinase that, when expressed at high levels, transforms certain skin cells (for example, melanocytes) into tumors called melanomas. [ 137 ] [ 138 ] A third possible source of tumor antigens are proteins normally important for regulating cell growth and survival, that commonly mutate into cancer inducing ...