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Cerebellar degeneration is a condition in which cerebellar cells, otherwise known as neurons, become damaged and progressively weaken in the cerebellum. [1] There are two types of cerebellar degeneration; paraneoplastic cerebellar degeneration , and alcoholic or nutritional cerebellar degeneration. [ 2 ]
Treatment Unknown Pontocerebellar hypoplasia ( PCH ) is a heterogeneous group of rare neurodegenerative disorders caused by genetic mutations and characterised by progressive atrophy of various parts of the brain such as the cerebellum or brainstem (particularly the pons ). [ 1 ]
Anencephaly is the absence of a major portion of the brain, skull, and scalp that occurs during embryonic development. [1] It is a cephalic disorder that results from a neural tube defect that occurs when the rostral (head) end of the neural tube fails to close, usually between the 23rd and 26th day following conception. [2]
Cerebellar hypoplasia is characterized by reduced cerebellar volume, even though cerebellar shape is (near) normal. It consists of a heterogeneous group of disorders of cerebellar maldevelopment presenting as early-onset non–progressive congenital ataxia , hypotonia and motor learning disability .
This also explains why dyschronometria is seen more commonly in the elderly due to the deterioration of physical brain matter with age. Other probable causes for the deterioration of brain matter in the elderly include increased supranational activation, decreased cerebellar activation (which is consistent with fronto-cerebellar dissociation). [10]
The cerebellum is the brain's main control center for planning, adjusting, and executing movements of the body, the limbs and the eyes. It plays a major role in several forms of motor learning, including balance and posture. [3] In the past, the evidence for a role for the cerebellum in cognitive functions was rather weak. [4]
Dandy–Walker malformation (DWM), also known as Dandy–Walker syndrome (DWS), is a rare congenital brain malformation in which the part joining the two hemispheres of the cerebellum (the cerebellar vermis) does not fully form, and the fourth ventricle and space behind the cerebellum (the posterior fossa) are enlarged with cerebrospinal fluid.
Another treatment for obstructive hydrocephalus is an endoscopic third ventriculostomy (ETV). This surgery creates an opening in the floor of the third ventricle so that CSF flows directly to the basal cisterns. This treatment can shortcut any obstruction like aqueductal stenosis. This may or may not be appropriate based on individual anatomy.