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[9] [12] As a hormone, melatonin is released by the pineal gland and is involved in sleep–wake cycles. [9] [12] As a supplement, it is often used for the attempted short-term treatment of disrupted sleep patterns, such as from jet lag or shift work, and is typically taken orally.
Sleep factors Athens insomnia scale Sleep induction: 0: No problem: 1: Slightly delayed: 2: Markedly delayed: 3: Very delayed or did not sleep at all Awakenings during the night: 0: No problem: 1: Minor problem: 2: Considerable problem: 3: Serious problem or did not sleep at all Final awakening: 0: Not earlier: 1: A little earlier: 2: Markedly ...
The sleep disturbance causes clinically significant distress or impairment in social, occupational, educational, academic, behavioral, or other important areas of functioning. The sleep difficulty occurs at least three nights per week. The sleep difficulty is present for at least three months.
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Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
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