Search results
Results From The WOW.Com Content Network
High-Mobility Group or HMG is a group of chromosomal proteins that are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair. [ 1 ] History and name
HMG-box containing proteins only bind non-B-type DNA conformations (kinked or unwound) with high affinity. [1]HMG-box domains are found in some high mobility group proteins, which are involved in the regulation of DNA-dependent processes such as transcription, replication, and DNA repair, all of which require changing the conformation of chromatin. [3]
The Hyundai Motor Group (HMG; IPA: [ˈhjəːndɛ]; [2] stylized as HYUNDAI) is a South Korean chaebol (loosely similar to a multinational conglomerate but without a central holding company or ownership structure) [3] [4] headquartered in Seoul, South Korea.
Thus, the presence of anti-HMG CoA reductase antibodies in someone who uses a statin and has myopathy strongly supports the diagnosis. [3] CK levels increase to 10-100 times above normal (2000–20,000 IU/L) in more than 90% of cases.
HMGB1 has to interact with p53. [15] [16]HMGB1 is a nuclear protein that binds to DNA and acts as an architectural chromatin-binding factor. It can also be released from cells, an extracellular form in which it may bind to toll-like receptors (TLRs) or an inflammatory receptor called the receptor for advanced glycation end-products RAGE.
This page was last edited on 8 September 2022, at 18:20 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
The domain is most commonly found in the high mobility group (HMG) proteins, HMG14 and HMG17, however, it is also found in other proteins which bind to nucleosomes, e.g. NBP-45. NBP-45 is a nucleosomal binding protein, first identified in mice, [ 3 ] which is related to HMG14 and HMG17.
As a result, the enhanceosome also recruits non histone architectural transcription factors, called high-mobility group (HMG) proteins, which are responsible for regulating chromatin structure. [3] These factors do not bind to the enhancer, but instead are used to restructure the DNA to ensure that the genes can be accessed by the transcription ...