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Holman used simulated gastric specimens and found the Hemoccult test to have significant problems with non-specificity and false-positive results, whereas the Gastroccult test was very accurate. [12] Holman found that by 120 seconds after the developer was applied, the Hemoccult test was positive on all control samples.
The effectiveness of the RightSpotpH® Indicator has been validated through clinical studies. A significant study published in the International Journal of Emergency Medicine demonstrated that the device is sensitive and specific for determining intragastric pH levels below or above 5.5, a common threshold used for confirming nasogastric tube placement.
The stool guaiac test method may be preferable to fecal immunochemical testing (FIT) if there is a clinical concern about possible gastric or proximal upper intestinal bleeding. [37] However, although heme breakdown is less than globin during intestinal transit, false negative results can be seen with the stool guaiac tests due to degradation ...
Gastric aspiration and or lavage, where a tube is inserted into the stomach via the nose in an attempt to determine if there is blood in the stomach, if negative does not rule out an upper GI bleed [20] but if positive is useful for ruling one in. [14] Clots in the stool indicate a lower GI source while melana stools an upper one. [14]
Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever.
Fecal occult blood testing (FOBT), as its name implies, aims to detect subtle blood loss in the gastrointestinal tract, anywhere from the mouth to the colon.Positive tests ("positive stool") may result from either upper gastrointestinal bleeding or lower gastrointestinal bleeding and warrant further investigation for peptic ulcers or a malignancy (such as colorectal cancer or gastric cancer).
In adults the most common source of aspiration pneumonia is aspiration of oropharyngeal secretions or gastric contents. In children the most common cause is aspiration of infected amniotic fluid, or vaginal secretions. Severe periodontal or gingival diseases are important risk factors for establishment of an anaerobic pleuropulmonary infection.
The reliability of aspiration in the diagnosis of SIBO has been questioned as SIBO can be patchy and the reproducibility can be as low as 38 percent. Breath tests have their own reliability problems with a high rate of false positive. Some doctors factor in a patients' response to treatment as part of the diagnosis. [4]