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  2. Anti-Hu associated encephalitis - Wikipedia

    en.wikipedia.org/wiki/Anti-Hu_associated...

    Older studies suggested the antibodies caused the disease, pointing to the discovery of antibody deposition in the brain tissue of patients at autopsy. However, the injection of the antibodies into mice did not produce any disease, and the deposition of antibody was often not at the places where brain damage was greatest. [3]

  3. Anti-NMDA receptor encephalitis - Wikipedia

    en.wikipedia.org/wiki/Anti-NMDA_receptor...

    Anti-NMDA receptor encephalitis is a type of brain inflammation caused by antibodies. [4] Early symptoms may include fever, headache, and feeling tired. [1] [2] This is then typically followed by psychosis which presents with false beliefs (delusions) and seeing or hearing things that others do not see or hear (hallucinations). [1]

  4. MOG antibody disease - Wikipedia

    en.wikipedia.org/wiki/MOG_antibody_disease

    Anti-MOG antibodies have been described in some patients with NMOSD [15] [16] who were negative for the aquaporin 4 (AQP-4) antibody. However, most NMOSD is an astrocytopathy, specifically an AQP4 antibody-associated disease, whereas MOG antibody-associated disease is an oligodendrocytopathy, suggesting that these are two separate pathologic entities. [2]

  5. Mixed connective tissue disease - Wikipedia

    en.wikipedia.org/wiki/Mixed_connective_tissue...

    Two investigations have provided evidence that anti-RNP antibodies have a role in the development of MCTD by linking antibody emergence to clinical illness. [ 63 ] [ 64 ] Beyond antibody formation, B cells can serve in a variety of other important immunological pathways, including as antigen presentation, pathogenic cytokine secretion, and ...

  6. Timeline of immunology - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_immunology

    1957 – Discovery of interferon by Alick Isaacs and Jean Lindenmann [10] 1958–1962 – Discovery of human leukocyte antigens (Jean Dausset and others) 1959–1962 – Discovery of antibody structure (independently elucidated by Gerald Edelman and Rodney Porter) 1959 – Discovery of lymphocyte circulation (James Gowans)

  7. Graves' disease - Wikipedia

    en.wikipedia.org/wiki/Graves'_disease

    Graves' disease is an autoimmune disorder, in which the body produces antibodies that are specific to a self-protein - the receptor for thyroid-stimulating hormone. (Antibodies to thyroglobulin and to the thyroid hormones T3 and T4 may also be produced.) These antibodies cause hyperthyroidism because they bind to the TSHr and chronically ...

  8. Rh disease - Wikipedia

    en.wikipedia.org/wiki/Rh_disease

    The term "Rh Disease" is commonly used to refer to HDFN due to anti-D antibodies, and prior to the discovery of anti-Rh o (D) immune globulin, it was the most common type of HDFN. The disease ranges from mild to severe, and occurs in the second or subsequent pregnancies of Rh-D negative women when the biologic father is Rh-D positive.

  9. Autoimmune neutropenia - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_neutropenia

    Autoimmune neutropenia (AIN) is a form of neutropenia which is most common in infants and young children [1] where the body identifies the neutrophils as enemies and makes antibodies to destroy them. Primary autoimmune neutropenia, another name for autoimmune neutropenia, is an autoimmune disease first reported in 1975 that primarily occurs in ...

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