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Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria Mycobacterium leprae or Mycobacterium lepromatosis. [4] [7] Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. [4]
Aldo Castellani was the first to prepare a substance similar to lepromin while attempting to produce a leprosy vaccine. [6] [7] Kensuke Mitsuda worked with lepromin starting in 1916 and published the first paper on it in 1919 [8] However, he retained Ernest Reinhold Rost's earlier name leprolin and his original idea was to find a test that distinguishes leprosy patients from non-leprosy persons.
Mycobacterium leprae (also known as the leprosy bacillus or Hansen's bacillus) is one [a] of the two species of bacteria that cause Hansen's disease (leprosy), [1] a chronic but curable infectious disease that damages the peripheral nerves and targets the skin, eyes, nose, and muscles.
"Leprosy is an infection caused by the bacteria Mycobacterium leprae," Dr. Fox explains. "It is slow growing and it can take months to years to develop symptoms. "It is slow growing and it can ...
About 99% of the mass of the human body is made up of six elements: oxygen, carbon, hydrogen, nitrogen, calcium, and phosphorus. Only about 0.85% is composed of another five elements: potassium, sulfur, sodium, chlorine, and magnesium. All 11 are necessary for life.
It was applied topically (which was ineffective) or taken internally (more effective but nauseating and often rejected by people as worse than leprosy). [10] [17] [18] The ingredient that appears to produce antimicrobial activity is hydnocarpic acid, a lipophilic compound. It may act by being an antagonist of biotin. [19] American researcher ...
The illness can be cured if treatment is completed as prescribed. What if you don't get treated for leprosy? If left untreated, nerve damage can result in paralysis and crippling of hands and feet.
This has made venoms a subject of study for people who work in drug discovery. [2] With developments in omic technologies (proteomics, genomics, etc.), researchers in this field became able to identify genes that produce certain elements in an animal's venom, as well as protein domains that have been used as building blocks across many species. [2]