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Drug dependence is an adaptive state associated with a withdrawal syndrome upon cessation of repeated exposure to a stimulus (e.g., drug intake). [ 57 ] [ 58 ] [ 59 ] Dependence is a component of a substance use disorder.
It is considered one of the most dangerous withdrawals of any known addictive substance. Similarly to benzodiazepines, the longer acting barbiturates produce a less severe withdrawal syndrome than short acting and ultra-short acting barbiturates. Withdrawal symptoms are dose-dependent with heavier users being more affected than lower-dose addicts.
In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. [2] A pharmaceutical drug , also called a medication or medicine, is a chemical substance used to treat , cure, prevent , or diagnose a disease or to promote well-being . [ 3 ]
Substance misuse, also known as drug misuse or, in older vernacular, substance abuse, is the use of a drug in amounts or by methods that are harmful to the individual or others. It is a form of substance-related disorder , differing definitions of drug misuse are used in public health , medical, and criminal justice contexts.
J&J has faced numerous civil lawsuits on behalf of children who were prescribed risperidone who grew breasts (a condition called gynecomastia); as of July 2016 there were about 1,500 cases in Pennsylvania state court in Philadelphia, and there had been a February 2015 verdict against J&J with $2.5 million awarded to a man from Alabama, a $1.75 ...
The amount of ethanol in the body is typically quantified by blood alcohol content (BAC); weight of ethanol per unit volume of blood. Small doses of ethanol, in general, are stimulant -like [ 61 ] and produce euphoria and relaxation; people experiencing these symptoms tend to become talkative and less inhibited, and may exhibit poor judgement.
Chinese troops surrounded, surprised, and overwhelmed the overextended and outnumbered American forces. The U.S. Army's X Corps, which included the 1st Marine Division and the Army's 7th Infantry Division regrouped and inflicted heavy casualties during their fighting withdrawal to the coast, known as the Battle of Chosin Reservoir.
Each year, high-income taxpayers must calculate and then pay the greater of an alternative minimum tax (AMT) or regular tax. [9] The alternative minimum taxable income (AMTI) is calculated by taking the taxpayer's regular income and adding on disallowed credits and deductions such as the bargain element from incentive stock options, state and local tax deduction, foreign tax credits, and ...