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Polonium in the body has a biological half-life of about 30 to 50 days. Caesium in the body has a biological half-life of about one to four months. Mercury (as methylmercury) in the body has a half-life of about 65 days. Lead in the blood has a half life of 28–36 days. [29] [30] Lead in bone has a biological half-life of about ten years.
The biological half life of tritiated water in the human body, which is a measure of body water turn-over, varies with the season. Studies on the biological half life of occupational radiation workers for free water tritium in a coastal region of Karnataka , India, show that the biological half life in the winter season is twice that of the ...
For example, the medical sciences refer to the biological half-life of drugs and other chemicals in the human body. The converse of half-life (in exponential growth) is doubling time. The original term, half-life period, dating to Ernest Rutherford's discovery of the principle in 1907, was shortened to half-life in the early 1950s. [1]
The plasma half-life or half life of elimination is the time required to eliminate 50% of the absorbed dose of a drug from an organism. Or put another way, the time that it takes for the plasma concentration to fall by half from its maximum levels.
Tritium (from Ancient Greek τρίτος (trítos) ' third ') or hydrogen-3 (symbol T or 3 H) is a rare and radioactive isotope of hydrogen with a half-life of ~12.3 years. The tritium nucleus (t, sometimes called a triton) contains one proton and two neutrons, whereas the nucleus of the common isotope hydrogen-1 (protium) contains one proton and no neutrons, and that of non-radioactive ...
Half maximal effective concentration (EC 50) is a measure of the concentration of a drug, antibody or toxicant which induces a biological response halfway between the baseline and maximum after a specified exposure time. [1] More simply, EC 50 can be defined as the concentration required to obtain a 50% [...] effect [2] and may be also written ...
The labeled [18 F]FDG compound has a relatively short shelf life which is dominated by the physical decay of fluorine-18 with a half-life of 109.8 minutes, or slightly less than two hours. Still, this half life is sufficiently long to allow shipping the compound to remote PET scanning facilities, in contrast to other medical radioisotopes like ...
In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral of the concentration of a drug in blood plasma as a function of time (this can be done using liquid chromatography–mass spectrometry [1]).