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Allantoin is a major metabolic intermediate in most organisms including animals, plants and bacteria, though not humans. It is produced from uric acid, which itself is a degradation product of nucleic acids, by action of urate oxidase (uricase). [3] [4] [5] Allantoin also occurs as a natural mineral compound (IMA symbol Aan [6]).
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It is a crystalline acid obtained by hydrolysis of allantoin. In nature, allantoic acid is produced from allantoin by the enzyme allantoinase (encoded by the gene AllB ( Uniprot : P77671 ) in Escherichia coli and other bacteria ).
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According to interviews given before she was exposed, she left her Brisbane family home at age 12 to live with a classmate and later lived with a family friend. [ 4 ] Gibson attended Wynnum State High School in Wynnum, Queensland , until dropping out in Year 10, [ 5 ] although she also later claimed to have been homeschooled .
Hydantoin can also be synthesized either by heating allantoin with hydroiodic acid or by "heating bromacetyl urea with alcoholic ammonia". [6] The cyclic structure of hydantoins was confirmed by Dorothy Hahn 1913. [7] Of practical importance, hydantoins are obtained by condensation of a cyanohydrin with ammonium carbonate. Another useful route ...
In enzymology, an allantoinase (EC 3.5.2.5) is an enzyme that catalyzes the chemical reaction (S)-allantoin + H 2 O allantoate. Thus, the two substrates of this enzyme are (S)-allantoin and H 2 O, whereas its product is allantoate.