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A number of such organisms are currently being investigated for their use as treatment, including: Trichuris suis ova, [6] [7] commonly known as pig whipworm eggs; Necator americanus, [8] commonly known as hookworms; Trichuris trichiura ova, [9] commonly referred to as human whipworm eggs; and Hymenolepis diminuta, commonly known as rat tapeworm.
Trichuris trichiura, Trichocephalus trichiuris or whipworm, is a parasitic roundworm (a type of helminth) that causes trichuriasis (a type of helminthiasis which is one of the neglected tropical diseases) when it infects a human large intestine.
Trichuriasis, also known as whipworm infection, is an infection by the parasitic worm Trichuris trichiura (whipworm). [2] If the infection is only with a few worms, there are often no symptoms. [ 1 ] In those who are infected with many worms, there may be abdominal pain , fatigue and diarrhea . [ 1 ]
Early signs include a cough, especially during or after exercise, and exercise intolerance. In the most advanced cases where many adult worms have built up in the heart without treatment, signs progress to severe weight loss, fainting, coughing up blood, and finally, congestive heart failure. [citation needed]
[8] [9] Currently, in some parts of Ethiopia where disease prevalence is high, up to 80% of people in a population lack access to washing facilities. While this is high, 93% did have access to a latrine, but only 29.2% of those latrines had proper construction to decrease parasitic infections. [ 9 ]
A novel drug tribendimidine, which was approved in China by the CCDC for human use in 2004, has been subjected to clinical trials showing that they are highly effective against major human flukes, ascaris (>90% cure rate) and hookworm (>82%); however with low cure rate for whipworm (<37%). [31]
The human whipworm, a parasitic worm. Because Hepatitis C virus (HCV) and the parasitic worm Schistosoma (the bloodfluke) are relatively common in developing countries, there are many cases where both are present in the human body. [21] According to Kamal, bloodflukes have been adequately shown to worsen HCV. [21]
The optimal duration of treatment for patients with disseminated infections is not clear. [10] Treatment of strongyloidiasis can be difficult and if ceasing treatment before being entirely cleared Strongyloides via the autoinfective cycle has been known to live in individuals for decades; [22] even after initial or inadequate sustained ...