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  2. Carbohydrate–insulin model - Wikipedia

    en.wikipedia.org/wiki/Carbohydrate–insulin_model

    The carbohydrate-insulin model (CIM) posits that obesity is caused by excess consumption of carbohydrate, which then disrupts normal insulin metabolism leading to weight gain and weight-related illnesses. It is contrasted with the mainstream energy balance model (EBM), which holds that obesity is caused by an excess in calorie consumption ...

  3. Insulin resistance - Wikipedia

    en.wikipedia.org/wiki/Insulin_resistance

    [38] [39] [40] Since insulin is the primary hormonal signal for energy storage into fat cells, which tend to retain their sensitivity in the face of hepatic and skeletal muscle resistance, insulin resistance stimulates the formation of new fatty tissue and accelerates weight gain. [2] In states of insulin resistance, beta cells in the pancreas ...

  4. Insulin signal transduction pathway - Wikipedia

    en.wikipedia.org/wiki/Insulin_signal...

    The insulin transduction pathway is a biochemical pathway by which insulin increases the uptake of glucose into fat and muscle cells and reduces the synthesis of glucose in the liver and hence is involved in maintaining glucose homeostasis. This pathway is also influenced by fed versus fasting states, stress levels, and a variety of other hormones.

  5. Hyperinsulinism - Wikipedia

    en.wikipedia.org/wiki/Hyperinsulinism

    Hyperinsulinism refers to an above normal level of insulin in the blood of a person or animal. Normal insulin secretion and blood levels are closely related to the level of glucose in the blood, so that a given level of insulin can be normal for one blood glucose level but low or high for another. Hyperinsulinism can be associated with several ...

  6. These 4 Factors Can Impact How Many Pounds You'll Lose on ...

    www.aol.com/4-factors-impact-many-pounds...

    In a new study, researchers identified four of the most important factors for long-term weight loss in patients taking a GLP-1 drug. These include the kind of medication, the dosage, the ...

  7. Disposition index - Wikipedia

    en.wikipedia.org/wiki/Disposition_index

    Changed from Cobelli et al. 2007 and Hannon et al. 2018 [1][2] The Disposition index (DI) is a measure for the loop gain of the insulin-glucose feedback control system. It is defined as the product of insulin sensitivity times the amount of insulin secreted in response to blood glucose levels. [3][4] "Metabolically healthy" Insulin resistant ...

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