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  2. Hyaluronic acid - Wikipedia

    en.wikipedia.org/wiki/Hyaluronic_acid

    Hyaluronic acid is a polymer of disaccharides, which are composed of D-glucuronic acid and N-acetyl-D-glucosamine, linked via alternating β-(1→4) and β-(1→3) glycosidic bonds. Hyaluronic acid can be 25,000 disaccharide repeats in length. Polymers of hyaluronic acid can range in size from 5,000 to 20,000,000 Da in vivo.

  3. Hyaluronidase - Wikipedia

    en.wikipedia.org/wiki/Hyaluronidase

    Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid. Karl Meyer classified these enzymes in 1971, into three distinct groups, a scheme based on the enzyme reaction products. [1] The three main types of hyaluronidases are two classes of eukaryotic endoglycosidase hydrolases and a prokaryotic lyase-type of ...

  4. Glycosaminoglycan - Wikipedia

    en.wikipedia.org/wiki/Glycosaminoglycan

    Hyaluronic acid binds cells together, lubricates joints, and helps maintain the shape of the eyeballs. [19] The viscoelasticity of hyaluronic acid makes it ideal for lubricating joints and surfaces that move along each other, such as cartilage. A solution of hyaluronic acid under low shear stress has a much higher viscosity than while under ...

  5. Is Hyaluronic Acid the Missing Ingredient in Your Hair Routine?

    www.aol.com/lifestyle/hyaluronic-acid-missing...

    Benefits of Hyaluronic Acid for Hair. As a serum or moisturizer, hyaluronic acid works by drawing water into the skin and keeping it there. “This miracle skincare ingredient is hydrophilic in ...

  6. Hyaluronan synthase - Wikipedia

    en.wikipedia.org/wiki/Hyaluronan_synthase

    proteins. Hyaluronan synthases (HAS) are membrane-bound enzymes that use UDP-α- N -acetyl- D -glucosamine and UDP-α- D -glucuronate as substrates to produce the glycosaminoglycan hyaluronan at the cell surface and extrude it through the membrane into the extracellular space.

  7. Extracellular matrix - Wikipedia

    en.wikipedia.org/wiki/Extracellular_matrix

    Glycosaminoglycans (GAGs) are carbohydrate polymers and mostly attached to extracellular matrix proteins to form proteoglycans (hyaluronic acid is a notable exception; see below). Proteoglycans have a net negative charge that attracts positively charged sodium ions (Na + ), which attracts water molecules via osmosis, keeping the ECM and ...

  8. Staphylococcus aureus - Wikipedia

    en.wikipedia.org/wiki/Staphylococcus_aureus

    Staphylococcus aureus produces various enzymes such as coagulase (bound and free coagulases) which facilitates the conversion of fibrinogen to fibrin to cause clots which is important in skin infections. [56] Hyaluronidase (also known as spreading factor) breaks down hyaluronic acid and helps in spreading it.

  9. Proteoglycan - Wikipedia

    en.wikipedia.org/wiki/Proteoglycan

    Proteoglycans are proteins [1] that are heavily glycosylated. The basic proteoglycan unit consists of a "core protein " with one or more covalently attached glycosaminoglycan (GAG) chain (s). [2] The point of attachment is a serine (Ser) residue to which the glycosaminoglycan is joined through a tetrasaccharide bridge (e.g. chondroitin sulfate ...