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Calcium metabolism is the movement and regulation of calcium ions (Ca 2+) in (via the gut) and out (via the gut and kidneys) of the body, and between body compartments: the blood plasma, the extracellular and intracellular fluids, and bone. Bone acts as a calcium storage center for deposits and withdrawals as needed by the blood via continual ...
Thus, a decrease in the phosphate concentration of the blood plasma (for a given total calcium concentration) increases the amount of calcium that is ionized. [ 20 ] [ 21 ] A third important effect of PTH on the kidney is its stimulation of the conversion of 25-hydroxy vitamin D into 1,25-dihydroxy vitamin D ( calcitriol ), which is released ...
Plasma membrane Ca. 2+. ATPase. The plasma membrane Ca2+ ATPase (PMCA) is a transport protein in the plasma membrane of cells that functions as a calcium pump to remove calcium (Ca 2+) from the cell. PMCA function is vital for regulating the amount of Ca 2+ within all eukaryotic cells. [1][2] There is a very large transmembrane electrochemical ...
Hyperphosphatemia. Hyperphosphatemia is an electrolyte disorder in which there is an elevated level of phosphate in the blood. [1] Most people have no symptoms while others develop calcium deposits in the soft tissue. [1] The disorder is often accompanied by low calcium blood levels, which can result in muscle spasms.
Calcium in biology. Calcium is used in many nerves in the voltage-gated calcium channel which is slightly slower than the voltage-gated potassium channel. It is most notably used in the cardiac action potential. [1] Calcium ions (Ca 2+) contribute to the physiology and biochemistry of organisms' cells. They play an important role in signal ...
Frequency. 2% (people in hospital) [1] Hypophosphatemia is an electrolyte disorder in which there is a low level of phosphate in the blood. [1] Symptoms may include weakness, trouble breathing, and loss of appetite. [1] Complications may include seizures, coma, rhabdomyolysis, or softening of the bones.
Phosphorus and sulfur are also common essential elements, essential to the structure of nucleic acids and amino acids, respectively. Chlorine, potassium, magnesium, calcium and phosphorus have important roles due to their ready ionization and utility in regulating membrane activity and osmotic potential . [ 2 ]
Calcium phosphate is the usual constitution of microcalcifications of the breast, particularly dystrophic calcifications. Microcalcifications as can be seen on mammography can be an early sign of breast cancer. Based on morphology, it is possible to classify by radiography how likely microcalcifications are to indicate cancer. [7]