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Povidone-iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine. [4] The recommended strength solution contains 10% Povidone, with total iodine species equaling 10,000 ppm or 1% total titratable iodine. [ 4 ]
It initially came into use as a disinfectant and a treatment for goiter. [6] [7] The following forms of iodine are found on the World Health Organization's List of Essential Medicines: [8] Potassium iodide [8]: 18, 42, 43 Amidotrizoate [8]: 40 Iohexol [8]: 40 Meglumine iotroxat [8]: 41 Povidone iodine [8]: 41
Medical iodophor (Chinese povidone-iodine solution) An iodophor is a preparation containing iodine complexed with a solubilizing agent, such as a surfactant or water-soluble polymers such as povidone (forming povidone-iodine), [1] [2] The result is a water-soluble material that releases free iodine when in solution.
Skin disinfection may be accomplished with a number of solutions including providone-iodine, chlorhexidine, alcohol based solutions, and cetrimide. [2] There is strong evidence that chlorhexidine and denatured alcohol use to clean skin prior to surgery is better than any other commercially available antiseptic, such as povidone-iodine with alcohol.
Allergies to povidone-iodine or shellfish do not affect the risk of side effects more than other allergies. [6] Use in the later part of pregnancy may cause hypothyroidism in the baby. [7] Iohexol is an iodinated non-ionic radiocontrast agent. [4] It is in the low osmolar family. [8] Iohexol was approved for medical use in 1985. [9]
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