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For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]
Guidelines on the choice of agents and how best to step up treatment for various subgroups in hypertension (high blood pressure) have changed over time and differ between countries. A Comparison of International Guidelines on Goal Blood Pressure and Initial Therapy for Adults With Hypertension (adapted from JNC 8 guidelines [ 1 ] )
Orthostatic hypertension involving the systolic BP is known as systolic orthostatic hypertension. High diastolic blood pressure measured while standing in a person who stood up shortly after waking up. When it affects an individual's ability to remain upright, orthostatic hypertension is considered as a form of orthostatic intolerance.
The dangerous effects of high blood pressure are highlighted in a new report by the World Health Organization that identifies the condition as one of the world’s leading risk factors for death ...
In the United States, the JNC8 (Eighth Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure) recommends thiazide-type diuretics to be one of the first-line drug treatments for hypertension, either as monotherapy or in combination with calcium channel blockers, ACEis, or ARBs. [7]
Variation in blood pressure that is significantly greater than the norm is known as labile hypertension and is associated with increased risk of cardiovascular disease [63] brain small vessel disease, [64] and dementia [65] independent of the average blood pressure level.