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De Quervain's thyroiditis, also known as subacute granulomatous thyroiditis or giant cell thyroiditis, is a self-limiting inflammatory illness of the thyroid gland. [1] De Quervain thyroiditis is characterized by fever , flu-like symptoms , a painful goiter , and neck pain .
In subacute granulomatous thyroiditis, a prodrome of a viral illness, painful thyroid, and symptoms of thyrotoxicosis may be present. [1] [2] [3] Thyroid function test will evolve through the three phases of thyrotoxicosis, hypothyroidism, and euthyroid state. In the thyrotoxic phase, thyroid stimulating hormone (TSH) will be low with high or ...
Acute infectious thyroiditis, Microbial inflammatory thyroiditis, Suppurative thyroiditis, [3] Pyrogenic thyroiditis, Bacterial thyroiditis [5] Cause: Bacterial, Parasitic, Fungal [ 3 ] de Quervain's thyroiditis , Subacute granulomatous thyroiditis, [ 3 ] Giant-cell thyroiditis, Pseudogranulomatous thyroiditis, Painful subacute thyroiditis, [ 5 ]
Thyroiditis is generally caused by an immune system attack on the thyroid, resulting in inflammation and damage to the thyroid cells. This disease is often considered a malfunction of the immune system and can be associated with IgG4-related systemic disease, in which symptoms of autoimmune pancreatitis, retroperitoneal fibrosis and noninfectious aortitis also occur.
Both of these entities can be considered subtypes of Hashimoto's thyroiditis and have an autoimmune basis. Anti-thyroid antibodies are common in all three and the underlying histology is similar. [1] [2] This disorder should not be confused with de Quervain's thyroiditis which is another form of subacute thyroiditis.
Toxic multinodular goiter (TMNG), also known as multinodular toxic goiter (MNTG), is an active multinodular goiter associated with hyperthyroidism.. It is a common cause of hyperthyroidism [2] [3] in which there is excess production of thyroid hormones from functionally autonomous thyroid nodules, which do not require stimulation from thyroid stimulating hormone (TSH).