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[43] [failed verification] UVC is the highest-energy, most-dangerous type of ultraviolet radiation, and causes adverse effects that can variously be mutagenic or carcinogenic. [44] Despite the importance of the sun to vitamin D synthesis, it is prudent to limit the exposure of skin to UV radiation from sunlight [45] and from tanning beds. [46]
The location of 'far-UVC' radiation (200-235 nm) in the electromagnetic spectrum. Far-UVC is a type of ultraviolet germicidal irradiation being studied and commercially developed for its combination of pathogen inactivation properties and reduced negative effects on human health when used within exposure guidelines. [1] [2] [3] [4]
The link between sun exposure and skin cancer is well established. Ultraviolet radiation is thought to cause up to 95% of basal and squamous cell carcinomas, and between 70-95% of melanomas in ...
Prolonged exposure to ultraviolet radiation from the sun can lead to melanoma and other skin malignancies. [4] Clear evidence establishes ultraviolet radiation, especially the non-ionizing medium wave UVB, as the cause of most non-melanoma skin cancers, which are the most common forms of cancer in the world. [4]
One of the largest promoters of apoptosis is exposure to ultraviolet (UV) light. While UV light is essential to human life it can also cause harm by inducing cancer, immunosuppression, photoaging, inflammation, and cell death. [1] Of the various components of sunlight, ultraviolet radiation B (UVB) (290-320 nm) is considered to be the most harmful.
Ultraviolet radiation is known to suppress the immune system and reduce inflammatory responses. Light therapy for skin conditions like psoriasis usually use 313 nanometer UVB though it may use UVA (315–400 nm wavelength) or a broader spectrum UVB (280–315 nm wavelength). UVA combined with psoralen, a drug taken orally, is known as PUVA ...
This reduces the treatment time, makes the treatment more effective, and enables the use of a weaker psoralen. The physician and physiotherapists can choose a starting dose of UV based on the patient's skin type. The UV dose will be increased in every treatment until the skin starts to respond, normally when it becomes a little bit pink.
To date, there is no link between an increase in a patient's risk of skin cancer and the proper use of narrow-band UVB phototherapy. [1] [2] "Proper use" is generally defined as reaching the "Sub-Erythemic Dose" (S.E.D.), the maximum amount of UVB your skin can receive without burning. Certain fungal growths under the toenail can be treated ...