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Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors. [1] [2] The term neurosteroid was coined by the French physiologist Étienne-Émile Baulieu and refers to steroids synthesized in ...
This is a list of neurosteroids, or natural and synthetic steroids that are active on the mammalian nervous system through receptors other than steroid hormone receptors. It includes inhibitory , excitatory , and neurotrophic neurosteroids as well as pheromones and vomeropherines .
Pregnenolone and its 3β-sulfate, pregnenolone sulfate, like dehydroepiandrosterone (DHEA), DHEA sulfate, and progesterone, belong to the group of neurosteroids that are found in high concentrations in certain areas of the brain, and are synthesized there. Neurosteroids affect synaptic functioning, are neuroprotective, and enhance myelinization.
One of the major areas of research within neurochemistry is looking at how post-traumatic stress disorder alters the brain. Neurotransmitter level fluctuations can dictate whether a PTSD episode occurs and how long the episode lasts. Dopamine has less of an effect than norepinephrine. Different neurochemicals can affect different parts of the ...
The principal cell type found in the claustrum is the Golgi type I neuron, which is a large cell with dendrites covered in spines. [ 9 ] [ 8 ] Through interhemispheric connections, the claustrum is believed to play a role in synchronizing activity in widely separated, but functionally related, parts of the brain such as between frontal eye ...
Pages in category "Neurosteroids" The following 65 pages are in this category, out of 65 total. This list may not reflect recent changes. ...
The latest research looked at a part of the brain called the olfactory bulb, which processes information about smell. Humans have two olfactory bulbs, one above each nasal cavity. Humans have two ...
The rest of the brain tissue is the structural stroma that includes connective tissue such as the meninges, blood vessels, and ducts. The two main types of cells in the brain are neurons, also known as nerve cells, and glial cells, also known as neuroglia. [1] There are many types of neuron, and several types of glial cell.