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Some researchers are investigating how metformin, a common drug used to treat diabetes, may help prolong healthspan and lifespan. What evidence is there to support this notion?
2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.
A 2017 review found that people with diabetes who were taking metformin had lower all-cause mortality. [231] They also had reduced cancer and cardiovascular disease compared with those on other therapies. [231] In people without diabetes, metformin does not appear to reduce the risk of cancer and cardiovascular disease. [237]
Symptoms of lactic acidosis include nausea, vomiting, and weakness. ... Stomach pain. Lightheadedness. Muscle pain. Shortness of breath. ... Taking metformin may cause unpleasant side effects like ...
Other symptoms include increased hunger, having a sensation of pins and needles, and sores (wounds) that heal slowly. [3] Symptoms often develop slowly. [ 6 ] Long-term complications from high blood sugar include heart disease , stroke , diabetic retinopathy , which can result in blindness , kidney failure , and poor blood flow in the lower ...
The medication most commonly may cause stomach upset and symptoms such as diarrhea but in general is well tolerated and has a relatively low chance of causing hypoglycemia. [35] One rare (about 1% chance) but serious side affect of metformin is that it can cause lactic acidosis, usually in patients with poor kidney function. [35]
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