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[10] [5] It appears to be generally safe in pregnancy. [5] It is of the lincosamide class and works by blocking bacteria from making protein. [5] Clindamycin was first made in 1966 from lincomycin. [11] [12] It is on the World Health Organization's List of Essential Medicines. [13] It is available as a generic medication.
It contains clindamycin, as the phosphate, a lincosamide antibacterial; adapalene, a synthetic retinoid; and benzoyl peroxide, an oxidizing agent. [2] It is applied to the skin . [ 2 ]
Gestational age: 6 weeks and 0 days until 6 weeks and 6 days old. 43–49 days from last menstruation. Embryonic age: Week nr 5. 4 weeks old. 29–35 days from fertilization. The embryo measures 8 mm (0.31 in) in length and weighs about 1 gram. [4] Optic vesicles and optic cups form the start of the developing eye. Nasal pits form.
Clindamycin/benzoyl peroxide, sold under the brand name Benzaclin among others, is a topical gel used for the treatment of acne. [7] It is a fixed-dose combination of clindamycin , as the phosphate, an antibiotic ; and benzoyl peroxide , an antiseptic .
[12] [14] If the woman has a severe allergy to beta-lactams and the GBS isolated is susceptible to clindamycin then clindamycin is the recommended alternative. [14] For women with a high-risk penicillin allergy and whose GBS isolate is not susceptible to clindamycin intravenous vancomycin (20 mg/kg intravenously every 8 hours, with a maximum of ...
Combined oral contraceptive pills are a type of oral medication that were originally designed to be taken every day at the same time of day in order to prevent pregnancy. [26] [37] There are many different formulations or brands, but the average pack is designed to be taken over a 28-day period (also known as a cycle). [citation needed] For the ...
Out of the many families of multidrug resistance pumps, lincosamides are most commonly shunted through pumps belonging to the resistance-nodulation-cell division superfamily. [17] Staphylococci express efflux pumps with specificity for 14 and 15 member ring macrolides and streptogramin B, but not lincosamide molecules.
When used to avoid pregnancy, the standard days method has been estimated [22] to have perfect-use efficacy of 95% and typical-use efficacy of 88%. [ 20 ] [ 21 ] These figures are based on a 2002 study in Bolivia, Peru, and the Philippines of women of reproductive age having menstrual cycles between 26 and 32 days, [ 20 ] [ 23 ] : 505 and on a ...