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The spinothalamic tract is a nerve tract in the anterolateral system in the spinal cord. [1] This tract is an ascending sensory pathway to the thalamus.From the ventral posterolateral nucleus in the thalamus, sensory information is relayed upward to the somatosensory cortex of the postcentral gyrus.
The substantia gelatinosa is one point (the nucleus proprius being the other) where first order neurons of the spinothalamic tract synapse. Many μ and κ-opioid receptors , presynaptic and postsynaptic , are found on these nerve cells; they can be targeted to manage pain of distal origin.
Crude touch (non-discriminating) is a sensory modality that allows the subject to sense that something has touched them, without being able to localize where they were touched (contrasting "fine touch"). Its fibres are carried in the spinothalamic tract, unlike the fine touch, which is carried in the dorsal column.
The spinothalamic tract is a sensory pathway originating in the spinal cord. It transmits information to the thalamus about pain, temperature, itch and crude touch . There are two main parts: the lateral spinothalamic tract , which transmits pain and temperature, and the anterior (or ventral) spinothalamic tract , which transmits crude touch ...
Ventral posterolateral nucleus, which receives sensory information from the body via the medial lemniscus, and spinothalamic tracts. Ventral posteromedial nucleus , which receives sensory information from the head and face via the trigeminal nerve .
The first-order neuron is a pseudounipolar neuron (shown left), with a single axon originating from the cell body then splitting into two branches. The body is situated in the dorsal root ganglion, with one axon traveling peripherally to tissue, and one traveling into the dorsal column. On the right is a bipolar neuron.
The Lissauer's tract will synapse on first-order neurons in grey matter of the dorsal horn, one or two vertebral levels up. The axons of these second-order neurons then decussate, joining the spinothalamic tract as they ascend to neurons in the ventral posterolateral nucleus of the thalamus.
The spinohypothalamic tract or spinohypothalamic fibers is a sensory fiber tract projecting from the spinal cord to the hypothalamus directly to mediate reflex autonomic and endocrine responses to painful stimuli (the hypothalamus receives additional indirect nociceptive projections from the reticular formation (see: spinoreticular tract), and periaqueductal gray (see: spinomesencephalic tract).