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Free-living amoebae (or "FLA") [1] are a group of protozoa that are important causes of infectious disease in humans and animals. Naegleria fowleri is often included in the group "free-living amoebae", [2] [3] and this species causes a usually fatal condition traditionally called primary amoebic meningoencephalitis (PAM).
Clockwise from top right: Amoeba proteus, Actinophrys sol, Acanthamoeba sp., Nuclearia thermophila., Euglypha acanthophora, neutrophil ingesting bacteria. An amoeba (/ ə ˈ m iː b ə /; less commonly spelled ameba or amœba; pl.: amoebas (less commonly, amebas) or amoebae (amebae) / ə ˈ m iː b i /), [1] often called an amoeboid, is a type of cell or unicellular organism with the ability ...
The most important genera are Amoeba and Chaos, which are set apart from the others by longitudinal ridges. The best known of the species in this family is Amoeba proteus, commonly used in classrooms to demonstrate movement by pseudopodia.
Amoebozoa includes many of the best-known amoeboid organisms, such as Chaos, Entamoeba, Pelomyxa and the genus Amoeba itself. Species of Amoebozoa may be either shelled (testate) or naked, and cells may possess flagella. Free-living species are common in both salt and freshwater as well as soil, moss and leaf litter.
Endolimax is a genus of amoebozoa [1] that are found in the intestines of various animals, including the species E. nana found in humans. Originally thought to be non-pathogenic, studies suggest it can cause intermittent or chronic diarrhea.
The amoeba can 'bore' into the intestinal wall, causing lesions and intestinal symptoms, and it may reach the bloodstream or peritoneal cavity. [8] From there, it can reach vital organs of the human body, usually the liver, but sometimes the lungs, brain, and spleen. [ 9 ]
This amoeba is said to rarely infect humans, but recently this has changed. It is in question as to whether it is pathogenic or not. [2] Despite some sources stating this is a free living amoeba, various studies worldwide have shown it contains the ability to infect humans, with some cases of pathogenic potential being reported. [3]
In Amoeba, the pseudopodia are approximately tubular, and rounded at the ends (lobose). The cell's overall shape may change rapidly as pseudopodia are extended and retracted into the cell body. An Amoeba may produce many pseudopodia at once, especially when freely floating. When crawling rapidly along a surface, the cell may take a roughly ...