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All ETS (Erythroblast Transformation Specific) family members are identified through a highly conserved DNA binding domain, the ETS domain, which is a winged helix-turn-helix structure that binds to DNA sites with a central GGA(A/T) DNA sequence.
ETS1 binds with DNA-dependent protein kinase (DNA-PK) [where the DNA-PK complex is made up of DNA-PKcs and DNA repair Ku (protein), and where Ku itself is a heterodimer of two polypeptides, Ku70 (XRCC6) and Ku80 (XRCC5)]. [17] ETS1 interaction with DNA-PK phosphorylates ETS1. [17] Such phosphorylation of ETS1 alters its target gene repertoire. [18]
Euro Truck Simulator (known as Big Rig Europe in North America) is a 2008 truck simulation game developed and published by SCS Software.The game is set in a scaled-down rendition of Europe, from the United Kingdom and Portugal to Poland and the Czech Republic, where players drive a variety of semi-trucks and trailers across the continent, visiting the continent's major cities, picking up and ...
A hard disk drive failure occurs when a hard disk drive malfunctions and the stored information cannot be accessed with a properly configured computer. A hard disk failure may occur in the course of normal operation, or due to an external factor such as exposure to fire or water or high magnetic fields , or suffering a sharp impact or ...
The fastest high-end server drives of 2010 had a seek time around 4 ms. [14] Some mobile devices have 15 ms drives, with the most common mobile drives at about 12 ms [15] and the most common desktop drives typically being around 9 ms. Two other less commonly referenced seek measurements are track-to-track and full stroke.
This technique when combined with high throughput sequencing is known as ChIP-Seq and when combined with microarrays it is known as ChIP-chip. Yeast one-hybrid System (Y1H) is used to identify which protein binds to a particular DNA fragment. Bacterial one-hybrid system (B1H) is used to identify which protein binds to a particular DNA fragment.
High density (HD) 3½-inch disks switch to a cobalt disk coating, just as with 5¼-inch HD disks. Drives use 700-oersted write heads for a density of 17,434 bpi. Extra-high density (ED) doubles the capacity over HD by using a barium ferrite coating and a special write head that allows the use of perpendicular recording. [1] [2]
An initial HPA could then be set (by some jumpers on the hard disk) to limit the number of cylinders to 4095 or 4096 so that the older BIOS would start. It was then the job of the bootloader to reset the HPA so that the operating system would see the full hard-disk storage space.