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Bis(chloroethyl) ether can be used in the synthesis of the cough suppressant fedrilate. It is combined with benzyl cyanide and two molar equivalents of sodamide in a ring-forming reaction. When treated with strong base, it gives divinyl ether, an anesthetic: [5] O(CH 2 CH 2 Cl) 2 + 2 KOH → O(CH=CH 2) 2 + 2 KCl + 2 H 2 O
Bis(chloromethyl) ether is an organic compound with the chemical formula (ClCH 2) 2 O. It is a colourless liquid with an unpleasant suffocating odour and it is one of the chloroalkyl ethers. Bis(chloromethyl) ether was once produced on a large scale, but was found to be highly carcinogenic and thus such production has ceased.
Chemical structure of chloromethyl methyl ether (MOM-Cl) Chloroalkyl ethers are a class of organic compounds with the general structure R-O-(CH 2) n-Cl, characterized as an ether connected to a chloromethyl group via an alkane chain. Chloromethyl methyl ether (CMME) is an ether with the formula C H 3 OCH 2 Cl.
Bis(2-chloroethyl)ethylamine is the organic compound with the formula C 2 H 5 N(CH 2 CH 2 Cl) 2.Often abbreviated HN1, it is a powerful vesicant and a nitrogen mustard gas. HN1 was developed in the 1920s and 1930s to remove warts and later as a military agent.
In the United Kingdom, the environmental regulator permits only chemical additives which are classed as non hazardous to groundwater for fracturing fluids. [3] [4] [5] Operators are required to disclose the content of hydraulic fracturing fluids to the relevant environment agency [6] while the composition must be disclosed if the regulator demands it. [7]
Various chloroethylnitrosoureas (such as N, N'-bis (2-chloroethyl)nitrosourea, BCNU) have obtained a medical use in the field of malignant tumors. [2] It is hypothesized that the efficacy against cancer cells is based on the alkylability of guanine cytosine centers in the sequences of the genetic material, especially the oncogenes.
Bis(2-chloroethyl)sulfide is the organosulfur compound with the formula (ClCH 2 CH 2) 2 S. It is a prominent member of a family of cytotoxic and blister agents known as mustard agents. Sometimes referred to as mustard gas , the term is technically incorrect: bis(2-chloroethyl)sulfide is a liquid at room temperature.
Bis(chloromethyl) ketone is a substance which is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities. [3]