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More and more research is being done on psychedelics including LSD, psilocybin, and ketamine. Here's what we know and what we don't know yet.
As of 2022, psilocybin is the most commonly researched psychedelic due to its safety and low potential for abuse and dependence. [2] Clinical trials are being conducted at universities and there is evidence confirming the use of psilocybin in the treatment of depression, post-traumatic stress disorder (PTSD) and end of life anxiety.
In the right context, “psychedelics can get the brain out of a state of depression or anxiety, a cycle of negative thoughts, self-perception, moods and behaviors,” Siegel said.
Psychedelic therapy (or psychedelic-assisted therapy) is the proposed use of psychedelic drugs to treat mental disorders. [59] As of 2021, psychedelic drugs are controlled substances in most countries and psychedelic therapy is not legally available outside clinical trials, with some exceptions. [34] [60]
2C-B (4-bromo-2,5-dimethoxyphenethylamine), also known as Nexus, is a synthetic psychedelic drug of the 2C family, mainly used as a recreational drug. [2] [1] [4] It was first synthesized by Alexander Shulgin in 1974 for use in psychotherapy.
Federal health regulators are questioning the safety and evidence behind the first bid to use MDMA, the mind-altering club drug, as a treatment for PTSD, part of a decadeslong effort by advocates ...
Recent studies have shown Nymphaea caerulea to have psychedelic properties, and may have been used as a sacrament in ancient Egypt and certain ancient South American cultures. Dosages of 5 to 10 grams of the flowers induces slight stimulation, a shift in thought processes, enhanced visual perception, and mild closed-eye visuals. [ 142 ]
The 2024 report by the RAND Corporation suggests psilocybin mushrooms may be the most prevalent psychedelic drug among adults in the United States. [196] In European countries, the lifetime prevalence estimates of psychedelic mushroom usage among young adults (15–34 years) range from 0.3% to 14.1%. [197]